History of Awards
Grant Round 18 - June 2025
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Nanotrap® SECURE (Sample Enrichment Concentration Universal RNA/DNA Extraction) Kit
University of Virginia and Virginia Tech Ceres Nanosciences (Manassas) $800,000 Developing a first-in-class humanized monoclonal antibody for immune modulation in human diseases University of Virginia and Virginia Commonwealth University HTIC, Inc. (Charlottesville) $800,000 Transforming epidural placement with precision-guided technology to enhance safety and patient satisfaction University of Virginia and Virginia Commonwealth University RIVANNA Medical, Inc. (Charlottesville) $800,000 |
Grant Round 17 - September 2024
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Adenosine A2B receptor blockade for the treatment of Clostridium difficile infection (CDI)
University of Virginia and Virginia Tech Adovate, LLC (Charlottesville, VA) $800,000 Anti-bioflim enzyme (ABE) as a novel, non-toxic solution that overcomes antimicrobial resistance to protect human health from farm to fork University of Virginia and Virginia Tech Lytos Technologies, LLC (Charlottesville, VA) $800,000 Orthopaedic Surgical Site Infection Prevention via an Antibiotic Releasing Click Hydrogel Virginia Commonwealth University and George Mason University Pascal Medical Corporation (Richmond, VA) $800,000 Investigational New Drug Enabling Studies of STX2310 Virginia Tech and University of Virginia S1P Therapeutics Inc. (Blacksburg, VA) $800,000 |
Grant Round 16 - April 2024
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Readmission Risk Assessment through Physiological and Behavioral Health Monitoring using
VitalStream Wireless Platform University of Virginia and Virginia Tech Caretaker Medical (Charlottesville, VA) $800,000 Optimization and Commercialization of PRECYSE as a Novel Quality Control Solution for Next Generation Sequencing Virginia Commonwealth University and University of Virginia Evizia, Inc. (Charlottesville, VA) $800,000 Developing an exercise-mimetic to treat diabetes University of Virginia and Virginia Tech MGMedicine, Inc. (Charlottesville, VA) $780,000 First-in-Class Bifunctional Cytokine to Target Tissue Resident Tregs for the Treatment of Idiopathic Nephropathy and other Autoimmune Diseases University of Virginia and Virginia Commonwealth University SlateBio, Inc. (Charlottesville, VA) $800,000 |
Grant Round 15 - September 2023
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Transforming Asthma Treatment with a New Generation A2B Adenosine Receptor Antagonist
University of Virginia and Virginia Tech Adovate, LLC (Charlottesville, VA) $800,000 Optimization of a Wearable Enteral Feeding System for Commercialization University of Virginia and Virginia Commonwealth University Luminoah, Inc. (Charlottesville, VA) $463,000 Pre-clinical Evaluation of an Implant Device for the Regeneration of Severe Osteochondral Defects, Utilizing a Proven Novel Material and 3D Printing Virginia Tech and University of Virginia Company: Nanochon, Inc. (Washington, DC) $445,000 Blocking the S1P Pathway for Chronic Kidney Disease Therapeutics Virginia Tech and University of Virginia S1P Therapeutics, Inc. (Blacksburg, VA) $500,000 |
Grant Round 14 - March 2023
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RNA Based Precision Medicine for Lupus Disease Management
Virginia Tech, University of Virginia AMPEL BioSolutions, LLC (Charlottesville, VA) $800,000 Commercialization of Intelligent Data-Driven Pulmonary Embolism Endovascular Therapy: The Versus Solution University of Virginia, Virginia Commonwealth University Liquet Medical, Inc. (Glen Allen, VA) $368,797 A Novel Platform for Treatment of High Dose Ionizing Radiation Virginia Tech, University of Virginia The Tiny Cargo Company (Roanoke, VA) $350,000 A Hybrid Alpha-pseudovirus, Multi-viral Nasal Vaccine Platform George Mason University, Virginia Tech Virongy Biosciences (Manassas, VA) $500,000 |
Grant Round 13 - May 2022
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Development of a Medical Device for Intraluminal Implantations of a Male Contraceptive Hydrogel
University of Virginia, Virginia Commonwealth University Contraline, Inc. (Charlottesville, VA) $700,000 Orthopedic Surgical Site Infection Prevention via Controlled, Sustained, Targeted, and Localized Antibiotic-Releasing Click Hydrogel Virginia Commonwealth University, George Mason University Pascal Medical Corp. (Richmond, VA) $375,000 Development of a First-in-Class Bifunctional Fusion Cytokine Therapy that Targets Tregs and Tissue Resident Tregs for the Treatment of Lupus and other Autoimmune Diseases University of Virginia, Virginia Commonwealth University, Virginia Tech Slate Bio, Inc. (Charlottesville, VA) $575,000 Preparing an Ultraound Enhanced Drug Delivery System for First-in-Human Studies University of Virginia, Virginia Commonwealth University SoundPipe Therapeutics (Charlottesville, VA) $600,000 |
Grant Round 12 - October 2021
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Optimization and Commercialization of Environmentally-Sustainable Biofungicides
Virginia Tech, University of Virginia AgroSpheres, Inc. (Charlottesville, VA) $600,000 Design Automation for Scaled Manufacturing of Advanced Custom Orthopedic Braces University of Virginia, Virginia Commonwealth University Icarus Medical Innovations (Charlottesville, VA) $600,000 Pilot Study to Evaluate a Nonsurgical Gel Patch for Eardrum Repair in Human Patients Eastern Virginia Medical School, Virginia Commonwealth University Tympanogen, Inc. (Richmond, VA) $737,369 |
Grant Round 11 - October 2020
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Clinical Translation of a Male Contraceptive Procedure
University of Virginia, Virginia Commonwealth University Contraline, Inc. (Charlottesville, VA) $600,000 Treating Chronic Disease Caused by Microbiome Dysbiosis George Mason University, Eastern Virginia Medical School ISOThrive, Inc. (Manassas, VA) $800,000 Innovative Bioanalytical Instrument for Improving Drug Discovery Virginia Commonwealth University, Old Dominion University Meru Biotechnologies (Richmond, VA) $700,000 |
Grant Round 10 - January 2020
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Microsystem for Label-Free Separation and Recovery of Tumor-Associated Cells
from Biopsies for Precision Medicine Virginia Tech, University of Virginia CytoRecovery Inc. (Blacksburg, VA) $400,000 Commercializing a Novel Treatment for Metastatic Cancers Virginia Commonwealth University, University of Virginia InterLeukin Combinatorial Therapies Inc. (Richmond, VA) $700,000 Design and Implementation of Green, Enzymatic Biofungicides for Pre- and Post-Harvest Crop Protection University of Virginia, Virginia Tech Lytos Technologies LLC (Charlottesville, VA) $500,000 Protein Painting of PD-1/PD-L1 for the Discovery of New Immune Checkpoint Inhibitors for the Treatment of Lung Cancer and Brain Metastasis George Mason University, Virginia Tech Monet Pharmaceuticals (Nokesville, VA) $400,000 Automated 3D Spinal Navigation System for Bedside Lumbar Puncture Procedures University of Virginia, Virginia Commonwealth University RIVANNA (Charlottesville, VA) $800,000 Development of an Applicator and Training Simulator for a Gel Patch for Nonsurgical Eardrum Repair Eastern Virginia Medical School, Virginia Commonwealth University Tympanogen (Richmond, VA) $500,000 |
Grant Round 9 - May 2019
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Agrospheres-Enabled Biological Fungicide
Virginia Tech, University of Virginia AgroSpheres Inc. (Charlottesville, VA) $600,000 Rapid Drug Development Using Molecular Rotational Resonance (MRR) for Structure Analysis Virginia Commonwealth University, University of Virginia, Virginia Tech BrightSpec Inc. (Charlottesville, VA) $400,000 Nanotrap Liquid Biopsy Collection Device (LBC) for Cancer Diagnostics University of Virginia, George Mason University Ceres Nanosciences Inc. (Manassas, VA) $600,000 Implementation and Clinical Impact of a Next Generation Precision Oncology Platform University of Virginia, Eastern Virginia Medical School Perthera Inc. (McLean, VA) $500,000 |
Grant Round 8 - May 2018
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MRR: A Major New Chiral Analysis Technique for Drug Discovery, Development and Process Control
Virginia Commonwealth University, Virginia Tech, University of Virginia BrightSpec Inc. (Charlottesville, VA) $400,000 Safe Mitochondrial Uncouplers for the Treatment of Human Disease Virginia Tech, University of Virginia Continuum Biosciences Inc. (Blacksburg, VA) $400,000 Biofabrication of Regenerative Musculoskeletal Therapeutics Old Dominion University, University of Virginia Embody Inc. (Norfolk, VA) $800,000 Tissue Preparations for Therapeutic Use in Cardiovascular Applications Old Dominion University, Eastern Virginia Medical School LifeNet Health (Virginia Beach, VA) $250,000 Novel Anti-Inflammatory Drug with Strong Neuroprotective Properties for Treatment of Traumatic Brain Injury (TBI) Virginia Commonwealth University, George Mason University Serpin Pharma (Manassas, VA) $350,000 Preventing Catheter Associated Infections Virginia Commonwealth University, University of Virginia WynnVision LLC (Richmond, VA) $510,000 |
Grant Round 7 - July 2017
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Virginia Brain Injury Diagnosis and Monitoring Initiative
Virginia Tech, University of Virginia BRAINBox Solutions, Inc. (Richmond, VA) $500,000 Novel Preventive Treatment Paradigm to Change the Standard of Care for Those Who Recover from Opioid Overdose Virginia Commonwealth University, Virginia Tech, George Mason University/ Inova Indivior, Inc. (Richmond, VA) $500,000 Development of Peptide Inhibitor of Complement C1 as a treatment for neonatal hypoxic-ischemic encephalopathy Eastern Virginia Medical School, Virginia Commonwealth University ReAlta Life Sciences, Inc. (Norfolk, VA) $400,000 |
Grant Round 6 - October 2016
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BT-11: First-in-class oral therapeutic for IBD
Virginia Tech, Virginia Commonwealth University BioTherapeutics, Inc. (Blacksburg, VA) VT, VCU $800,000 Bioengineering for the therapeutic delivery of massively expanded islet-derived human beta-cells Virginia Commonwealth University, University of Virginia Propagenix, Inc. (Rockville, MD) $425,000 Translational research with nanosecond pulsed electric fields for immuno-oncology applications Old Dominion University, Eastern Virginia Medical School Pulse Biosciences, Inc. (Burlingame, CA) $300,000 Accelerating the commercialization of the Diamond™ mouse model of NASH Eastern Virginia Medical School, George Mason University Sanyal Biotechnology (Richmond, VA) $100,000 Novel and potent anti-inflammatory drug with cardio-protective effects to treat myocardial injury and prevent heart failure George Mason University, Virginia Commonwealth University Serpin Parma (Manassas, VA) $400,000 Commercialization of INSPIRE brain cancer treatment Virginia Tech, University of Virginia VoltMed, Inc. (Blacksburg, VA) $800,000 |
Grant Round 5 - December 2015
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Development of a biomarker assay and protocol for the commercialization of mibefradil dihydrochloride as a first-line treatment for glioblastoma
University of Virginia, George Mason University, Yale University Cavion, LLC (Charlottesville, VA) $307,057 INSPIRE to fight brain cancer Virginia Tech, University of Virginia VoltMed, Inc. (Blacksburg, VA) $380,000 |
Grant Round 4 - August 2015
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Three wave mixing technique for chiral analysis in continuous process manufacturing
Virginia Commonwealth University, University of Virginia BrightSpec Inc. (Charlottesville, VA) $400,000 Optimizing oral delivery of BT-11 as a clinical candidate for treating inflammatory bowel disease Virginia Tech, Virginia Commonwealth University BioTherapeutics, Inc. (Blacksburg, VA) $400,000 Nanotrap® tick-panel test development George Mason University, Virginia Tech Ceres Nanosciences Inc. (Manassas, VA) $500,000 Nanofabrication of tissue scaffolds Old Dominion University, Eastern Virginia Medical School Embody, Inc. (Norfolk, VA) $634,500 Clinical trial of new drug in dogs to treat brain cancer in humans Virginia Tech, University of Virginia FirstString Research $290,000 |
Grant Round 3 - August 2014
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PhenoCHIP-phenotype-based cell hierarchy and isolation platform
Virginia Tech, University of Virginia Proteo Biosciences $270,000 Biomarker-driven optimization of IL-12 gene electrotransfer for the treatment of melanoma Old Dominion University, Eastern Virginia Medical School Onosec Medical $585,000 Ultrasonographic probe Virginia Commonwealth University, Old Dominion University Ultrasonic Probe $536,000 |
Grant Round 2 - March 2014
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Reversing bioenergetic deficits and improving cognitive function in Alzheimer’s Disease
Virginia Commonwealth University, University of Virginia Gencia Corporation $400,000 Enhancement of healing in diabetic wounds using a decellularized dermal matrix Eastern Virginia Medical School, University of Virginia LifeNet Health (Virginia Beach, VA) $255,000 UVA-VCU partnership to develop radioimmunotherapeutic and imaging agents to a unique cell-surface target relevant for multiple human cancers University of Virginia, Virginia Commonwealth University Neoantigenics $348,729 Lead optimization of a SphK2 inhibitor for the treatment of CKD Virginia Tech, University of Virginia SphynKx $400,000 |
Grant Round 1 - December 2013
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Development of novel anti-inflammatory drugs
Virginia Tech, Virginia Commonwealth University BioTherapeutics, Inc. (Blacksburg, VA) $400,000 Commercialization of a human tumor microenvironment system for pharmaceutical cancer drug discovery and development University of Virginia, George Mason University HemoShear Therapeutics, Inc. (Charlottesville, VA) $450,000 Novel regenerative drug Virginia Tech, University of Virginia FirstString Research (Mount Pleasant, SC) $200,000 Determining the optimal dosing schedule for the commercialization of mibefradil in front-line glioblastoma University of Virginia, Virginia Commonwealth University Tau Therapeutics: now Cavion, LLC (Charlottesville, VA) $200,000 |
